First, anticoagulants were approved only

First, anticoagulants were approved only for the prevention of stroke. But this market is very small. Therefore, the phase III study was conducted on more than 15,000 elderly patients to show that Xarelto® is not worse than warfarin. The treatment was present and approved in 2010 for the prevention of stroke, a market worth 20 million euros.

In 2011, Bayer managed to sell 0.7 million doses per day (only in Germany). After one year, there were 25.5 million daily doses, a sign of considerable experience in Bayer’s marketing management, but no medication agreed without restrictions.

In early 2012, the Federal Institute of Medicines and Medical Devices (BfArM) received 750 reports of negative comments on Xarelto, which included 58 deaths. In the first eight months of 2013, there were 968 negative events with 72 deaths, according to the Spiegel magazine at that time.

Of course, both BfArM and Bayer showed a distant causal relationship. So it’s just a coincidence, right?

Anticoagulants – side effects
It is known that the properties of blood have side effects. The main problem is the difficult dose, which must be determined individually for each individual. Therefore, it takes a while to adjust the correct dose. slimfast keto Even in this case, the situation can change repeatedly.

Because of this, many patients with coumarin need to go to the doctor at least once a month to register. Another part of the patient is able, with a meter (INR value) to control the capacity of the independent blood clot in the home and adjust the dose accordingly.

The INR is 1 or slightly lower in healthy people.

If the value increases without taking anticoagulants, there is a health problem. B – Lack of vitamin K: Because vitamin K regulates the ability of blood to clot. If missing, it is related to blood coagulation disorders.

If the blood is necessary to go back down now the taking of medicines (for the prevention of stroke and carrots), after taking medicines to prevent blood clots so that the INR value increases from 2 to 3. In some cases, the risk of stroke, especially high, the increase in the value from 3.5 to 4.5.

The value obtained by the medicine differs significantly from the correct blood value. The blood is more “diluted” than the correct blood. What’s the score? …

Leave a Reply

Your email address will not be published. Required fields are marked *