First, anticoagulants were approved only for the prevention

First, anticoagulants were approved only for the prevention of stroke. But this market is quite small. Therefore, the phase III study was conducted on more than 15,000 elderly patients to show that Xarelto® is not worse than warfarin. The treatment was present and approved in 2010 for the prevention of stroke, a market worth 20 million euros.

In 2011, Bayer managed to sell 0.7 million doses per day (only in Germany). After a year, there were 25.5 million daily doses – a sign of the great experience of Bayer’s marketing department, but do not agree on drugs without restrictions.

In early 2012, the Federal Institute for Medicines and Medical Devices received (BfArM) 750 reports of adverse reactions for Xarelto®, including 58 deaths. In the first eight months of 2013, there were 968 negative events with 72 deaths, according to Spiegel magazine at the time.

Of course, both BfArM and Bayer have shown a causal relationship ketozin away from them. So it’s just a coincidence, is not it?

Anticoagulants – side effects
It is known that the characteristics of blood have side effects. The main problem is the difficult dose, which must be determined individually for each individual. Therefore, it takes a while to “adjust” the correct dose. Even in this case, the situation can change again and again.

Because of this, many patients with coumarin need to go to the doctor at least once a month to register. Another part of the patient is able, with the (INR value) meter to control the ability of independent blood coagulation in the home and adjust the dose accordingly.

The international normal ratio (INR) is 1 or slightly lower in healthy people.

If the value increases without taking anticoagulants, there is a health problem. B. Vitamin K deficiency. Because vitamin K regulates the ability of blood to clot. If it is missing, it is about coagulation disorders.

If you need blood relieving now by taking medication (for the prevention of stroke and reflux), then the blood is taken thinner to the point of raising the INR value from 2 to 3. In some cases, the risk of stroke , especially high, the increase in the value of 3.5 to 4.5.

The value obtained by the drug differs significantly from the healthy blood value. The blood is more “diluted” than with the right blood. What’s the score?

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